Acidum etidronicum [INN-Latin]
Brand names,
Acidum etidronicum [INN-Latin]
Analogs
Acidum etidronicum [INN-Latin]
Brand Names Mixture
Acidum etidronicum [INN-Latin]
Chemical_Formula
C24H25NO4
Acidum etidronicum [INN-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Acidum etidronicum [INN-Latin]
fda sheet
Acidum etidronicum [INN-Latin]
msds (material safety sheet)
Acidum etidronicum [INN-Latin]
Synthesis Reference
No information avaliable
Acidum etidronicum [INN-Latin]
Molecular Weight
391.46 g/mol
Acidum etidronicum [INN-Latin]
Melting Point
No information avaliable
Acidum etidronicum [INN-Latin]
H2O Solubility
10 mg/L
Acidum etidronicum [INN-Latin]
State
Solid
Acidum etidronicum [INN-Latin]
LogP
4.636
Acidum etidronicum [INN-Latin]
Dosage Forms
Tablets (100 mg)
Acidum etidronicum [INN-Latin]
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Acidum etidronicum [INN-Latin]
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Acidum etidronicum [INN-Latin]
Absorption
Well absorbed from gastrointestinal tract.
Acidum etidronicum [INN-Latin]
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Acidum etidronicum [INN-Latin]
Patient Information
Acidum etidronicum [INN-Latin]
Organisms Affected
Humans and other mammals